Two feet-one hand syndrome
Medical condition / From Wikipedia, the free encyclopedia
Two feet-one hand syndrome (TFOHS), is a long-term fungal condition where athlete's foot or fungal toe nail infections in both feet is associated with tinea manuum in one hand.[3][7] Often the feet are affected for several years before symptoms of a diffuse scaling rash on the palm of one hand appear, which is when most affected people then seek medical help.[7]
Two feet-one hand syndrome | |
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Specialty | Dermatology, infectious diseases |
Symptoms | Diffuse scaling of palms and prominent palmar creases in one hand, tinea pedis in both feet[1] |
Complications | Secondary bacterial infection[2] |
Duration | Tendency to last longterm[3] |
Causes | Trichophyton rubrum[3] |
Risk factors | Excessive sweating[4] |
Diagnostic method | Visualization, microscopy, culture[4] |
Differential diagnosis | Dermatitis, psoriasis, keratoderma, hyperkeratosis, allergic contact dermatitis[5] |
Prevention | Foot hygiene,[4] avoid scratching feet and toes[6] |
Treatment | Antifungals[4] |
Medication | Oral terbinafine, itraconazole, fluconazole, griseofulvin[4] |
Frequency | Males>females[3] |
The most common causative organism is Trichophyton rubrum.[3] The condition is more likely to occur in people who sweat more.[4] Diagnosis is by visualization, microscopy and culture.[4] It may appear similar to dermatitis, psoriasis, keratoderma, hyperkeratosis and allergic contact dermatitis.[5] Treatment is with long-term systemic antifungals, typically oral terbinafine or itraconazole.[4][8]
The condition is frequently seen in skin clinics.[9] Males are affected more frequently than females.[3] One study showed that 65% of cases with tinea manuum were part of TFOHS.[6][10] TFOHS was first described by Curtis in 1964.[11]