Zofenopril
Antihypertensive drug of the ACE inhibitor class / From Wikipedia, the free encyclopedia
Zofenopril (INN) is a medication that protects the heart and helps reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor.[1]
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Trade names | Zocardis (RU) |
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Routes of administration | Oral |
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Formula | C22H23NO4S2 |
Molar mass | 429.55 g·mol−1 |
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In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs, atenolol and enalapril, and was associated with fewer adverse effects.[2][3]
Zofenopril is a prodrug with zofenoprilat as the active metabolite.[4]
It was patented in 1978 and approved for medical use in 2000.[5]