TCEA1
Human protein-coding gene / From Wikipedia, the free encyclopedia
Transcription elongation factor A protein 1 is a protein that in humans is encoded by the TCEA1 gene.[5][6][7]
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In other organisms, this gene is better known as transcription elongation factor II S (TFIIS). It mainly helps to resolve backtracked elongation complexes by inducing a cut in the RNAP active site, so reaction becomes possible again. It is also found in the eukaryotic transcription preinitiation complex.[8] A homolog in archaea performs the same main task, while bacteria use the non-homologous Gre.[9]