Sebaceous carcinoma
Medical condition / From Wikipedia, the free encyclopedia
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Sebaceous carcinoma, also known as sebaceous gland carcinoma (SGc), sebaceous cell carcinoma, and meibomian gland carcinoma is an uncommon malignant cutaneous tumor.[1] Most are typically about 1.4 cm at presentation.[2] SGc originates from sebaceous glands in the skin and, therefore, may originate anywhere in the body where these glands are found. SGc can be divided into 2 types: periocular and extraocular. The periocular region is rich in sebaceous glands making it a common site of origin.[3][4] The cause of these lesions in the vast majority of cases is unknown. Occasional cases may be associated with Muir-Torre syndrome.[5] SGc accounts for approximately 0.7% of all skin cancers, and the incidence of SGc is highest in Caucasian, Asian, and Indian populations.[2][6] Due to the rarity of this tumor and variability in clinical and histological presentation, SGc is often misdiagnosed as an inflammatory condition or a more common neoplasm.[6] SGc is commonly treated with wide local excision or Mohs micrographic surgery, and the relative survival rates at 5 and 10 years are 92.72 and 86.98%, respectively.[6]
Sebaceous carcinoma | |
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Micrograph of a sebaceous carcinoma (left of image) metastatic to the parotid gland (right of image). H&E stain. | |
Specialty | Oncology, dermatology |