Pyrazine
Chemical compound / From Wikipedia, the free encyclopedia
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Pyrazine is a heterocyclic aromatic organic compound with the chemical formula C4H4N2. It is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. It is a "deliquescent crystal or wax-like solid with a pungent, sweet, corn-like, nutty odour".[3]
Quick Facts Names, Identifiers ...
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Names | |||
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Preferred IUPAC name
Pyrazine[1] | |||
Other names
1,4-Diazabenzene, p-Diazine, 1,4-Diazine, Paradiazine, Piazine, UN 1325 | |||
Identifiers | |||
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3D model (JSmol) |
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ChEBI | |||
ChEMBL | |||
ChemSpider |
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ECHA InfoCard | 100.005.480 | ||
EC Number |
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PubChem CID |
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UNII | |||
CompTox Dashboard (EPA) |
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Properties | |||
C4H4N2 | |||
Molar mass | 80.09 g/mol | ||
Appearance | White crystals | ||
Density | 1.031 g/cm3 | ||
Melting point | 52 °C (126 °F; 325 K) | ||
Boiling point | 115 °C (239 °F; 388 K) | ||
Soluble | |||
Acidity (pKa) | 0.37[2] (protonated pyrazine) | ||
-37.6·10−6 cm3/mol | |||
Hazards | |||
GHS labelling: | |||
Danger | |||
H228, H315, H319, H335 | |||
P210, P261, P305+P351+P338 | |||
NFPA 704 (fire diamond) | |||
Flash point | 55 °C (131 °F; 328 K) c.c. | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anions and decrease nitric oxide production in human Granulocytes.[4]