Pimozide
Chemical compound / From Wikipedia, the free encyclopedia
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Pimozide (sold under the brand name Orap) is a neuroleptic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1). On a weight basis it is even more potent than haloperidol. It also has special indication for Tourette syndrome and resistant tics.
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Orap |
AHFS/Drugs.com | Monograph |
MedlinePlus | a686018 |
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Routes of administration | Oral |
Drug class | Typical antipsychotic |
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Bioavailability | 40-50% |
Metabolism | CYP3A4, CYP1A2 and CYP2D6 |
Elimination half-life | 55 hours (adults), 66 hours (children) |
Excretion | Urine |
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ECHA InfoCard | 100.016.520 |
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Formula | C28H29F2N3O |
Molar mass | 461.557 g·mol−1 |
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