Photolyase
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Photolyases (EC 4.1.99.3) are DNA repair enzymes that repair damage caused by exposure to ultraviolet light. These enzymes require visible light (from the violet/blue end of the spectrum) both for their own activation[1] and for the actual DNA repair.[2] The DNA repair mechanism involving photolyases is called photoreactivation. They mainly convert pyrimidine dimers into a normal pair of pyrimidine bases. Photo reactivation, the first DNA repair mechanism to be discovered, was described initially by Albert Kelner in 1949[3] and independently by Renato Dulbecco also in 1949.[4][5][6]
Cryptochrome/photolyase, C-terminal, FAD binding | |||||||||||
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Identifiers | |||||||||||
Symbol | FAD_binding_7 | ||||||||||
Pfam | PF03441 | ||||||||||
InterPro | IPR005101 | ||||||||||
PROSITE | PDOC00331 | ||||||||||
SCOP2 | 1qnf / SCOPe / SUPFAM | ||||||||||
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deoxyribodipyrimidine photo-lyase (CPD) | |||||||||
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Identifiers | |||||||||
EC no. | 4.1.99.3 | ||||||||
CAS no. | 37290-70-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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