Peutz–Jeghers syndrome
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Peutz–Jeghers syndrome (often abbreviated PJS) is an autosomal dominant genetic disorder characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa (melanosis).[2] This syndrome can be classed as one of various hereditary intestinal polyposis syndromes[3] and one of various hamartomatous polyposis syndromes.[4] It has an incidence of approximately 1 in 25,000 to 300,000 births.[5]
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Manifestations of Peutz–Jeghers syndrome[1] | |
Specialty | Medical genetics |
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