PTPN1
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene.[5] PTP1B is a negative regulator of the insulin signaling pathway and is considered a promising potential therapeutic target, in particular for treatment of type 2 diabetes.[6] It has also been implicated in the development of breast cancer and has been explored as a potential therapeutic target in that avenue as well.[7][8][9]
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