Nicotine replacement therapy
Treatment for tobacco use disorder / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Nicotine replacement therapy?
Summarize this article for a 10 year old
Nicotine replacement therapy (NRT) is a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco.[6] It is used to help with quitting smoking or stopping chewing tobacco.[1][7] It increases the chance of quitting tobacco smoking by about 55%.[8] Often it is used along with other behavioral techniques.[1] NRT has also been used to treat ulcerative colitis.[1] Types of NRT include the adhesive patch, chewing gum, lozenges, nose spray, and inhaler.[1] The use of multiple types of NRT at a time may increase effectiveness.[9][10]
Clinical data | |
---|---|
Trade names | Nicoderm, Commit, Nicorette, others[1] |
Other names | NRT |
AHFS/Drugs.com | Monograph |
MedlinePlus | a601084 |
License data | |
Routes of administration | Oral, Inhalation, Transdermal, |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Metabolites | Cotinine |
Excretion | renal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
Chemical and physical data | |
Formula | C10H14N2 |
Molar mass | 162.236 g·mol−1 |
Common side effects depend on the formulation of nicotine.[1] Common side effects with the gum include nausea, hiccups, and irritation of the mouth.[1] Common side effects with the patch include skin irritation and a dry mouth while the inhaler commonly results in a cough, runny nose, or headaches.[1] Serious risks include nicotine poisoning and continued addiction.[1] They do not appear to increase the risk of heart attacks.[8] There are possible harms to the baby if used during pregnancy.[1][11] Nicotine replacement therapy works by reducing cravings caused by nicotine addiction.[1][12]
They were first approved for use in 1984, in the United States.[1] Nicotine replacement products are on the World Health Organization's List of Essential Medicines.[13][14][15] They are available as generic medications.[1]