Membranoproliferative glomerulonephritis
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Membranoproliferative glomerulonephritis (MPGN) is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening,[2] activating the complement system and damaging the glomeruli.
Quick Facts Other names, Specialty ...
Membranoproliferative glomerulonephritis | |
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Other names | Mesangiocapillary glomerulonephritis[1] |
Micrograph of glomerulus in membranoproliferative glomerulonephritis with increased mesangial matrix and increased mesangial cellularity. Kidney biopsy. PAS stain. | |
Specialty | Nephrology |
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MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults.[3]
It should not be confused with membranous glomerulonephritis, a condition in which the basement membrane is thickened, but the mesangium is not.