Knorr pyrrole synthesis
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The Knorr pyrrole synthesis is a widely used chemical reaction that synthesizes substituted pyrroles (3).[1][2][3] The method involves the reaction of an α-amino-ketone (1) and a compound containing an electron-withdrawing group (e.g. an ester as shown) α to a carbonyl group (2).[4]
Quick Facts Identifiers ...
Knorr pyrrole synthesis | |
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Named after | Ludwig Knorr |
Reaction type | Ring forming reaction |
Identifiers | |
RSC ontology ID | RXNO:0000497 |
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