Karl Barry Sharpless
American chemist and Nobel Laureate (born 1941) / From Wikipedia, the free encyclopedia
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Karl Barry Sharpless (born April 28, 1941) is an American stereochemist. He is a two-time Nobel laureate in Chemistry known for his work on stereoselective reactions and click chemistry.
Karl Barry Sharpless | |
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Born | Karl Barry Sharpless (1941-04-28) April 28, 1941 (age 83) Philadelphia, Pennsylvania, U.S. |
Alma mater | Dartmouth College (BA) Stanford University (MS, PhD) |
Known for | |
Spouse |
Jan Dueser ā (m. 1965) |
Awards |
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Scientific career | |
Fields | Stereochemistry |
Institutions | |
Thesis | Studies of the Mechanism of Action of 2,3-oxidosqualene-lanosterol cyclase: Featuring Enzymic Cyclization of Modified Squalene Oxides (1968) |
Doctoral advisor | Eugene van Tamelen |
Doctoral students | M.G. Finn |
Other notable students | Undergrads: Post-docs: |
Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry".[1][2] Sharpless is the fifth person (in addition to two organizations), to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger).