Interleukin 12
Interleukin / From Wikipedia, the free encyclopedia
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Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells,[1] macrophages, neutrophils, helper T cells and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 belongs to the family of interleukin-12. IL-12 family is unique in comprising the only heterodimeric cytokines, which includes IL-12, IL-23, IL-27 and IL-35.[2] Despite sharing many structural features and molecular partners, they mediate surprisingly diverse functional effects.
Quick Facts Human Interleukin 12, Identifiers ...
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Quick Facts IL12A, Identifiers ...
IL12A | |||||||
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Identifiers | |||||||
Symbol | IL12A | ||||||
Alt. symbols | CLMF1, NKSF1, p35 | ||||||
NCBI gene | 3592 | ||||||
HGNC | 5969 | ||||||
OMIM | 161560 | ||||||
RefSeq | NM_000882 | ||||||
UniProt | P29459 | ||||||
Other data | |||||||
Locus | Chr. 3 p12-q13.2 | ||||||
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