IgA pemphigus
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IgA pemphigus is a subtype of pemphigus with two distinct forms:
- Subcorneal pustular dermatosis (also known as Sneddon–Wilkinson disease and pustulosis subcornealis)[1] is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils.[2][3]: 203 This is distinct from and not to be confused with subcorneal pustular dermatosis type of IgA pemphigus. Sneddon's syndrome, also known as Ehrmann-Sneddon syndrome, is also a different syndrome.[4]
- Intraepidermal neutrophilic IgA dermatosis is characterized histologically by intraepidermal bullae with neutrophils, some eosinophils, and acantholysis.[3]: 465
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IgA pemphigus | |
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Schematic of immunoglobulin A dimer showing H-chain (blue), L-chain (red), J-chain (magenta) and secretory component (yellow). | |
Specialty | Dermatology |
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