Homoplasmy
Identity of organellar DNA sequences in a cell / From Wikipedia, the free encyclopedia
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Not to be confused with Homoplasy.
Homoplasmy is a term used in genetics to describe a eukaryotic cell whose copies of mitochondrial DNA are all identical.[1] In normal and healthy tissues, all cells are homoplasmic.[2] Homoplasmic mitochondrial DNA copies may be normal or mutated;[1] however, most mutations are heteroplasmic[2][3] (only occurring in some copies of mitochondrial DNA). It has been discovered, though, that homoplasmic mitochondrial DNA mutations may be found in human tumors.[4]
The term may also refer to uniformity of plant plastid DNA, whether occurring naturally or otherwise.[citation needed]