Hemophagocytic lymphohistiocytosis
Immune disorder in the blood leading to hyperinflammation / From Wikipedia, the free encyclopedia
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In hematology, hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome,[1] is an uncommon hematologic disorder seen more often in children than in adults. It is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes. There are inherited and non-inherited (acquired) causes of HLH.
Quick Facts Other names, Specialty ...
Hemophagocytic lymphohistiocytosis | |
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Other names | HLH |
Micrograph showing red blood cells within macrophages. H&E stain. | |
Specialty | Hematology, immunology |
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