Desmosine
Chemical compound / From Wikipedia, the free encyclopedia
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Desmosine is an amino acid found uniquely in elastin, a protein found in connective tissue such as skin, lungs, and elastic arteries.
Quick Facts Names, Identifiers ...
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IUPAC name
6-{4-[(4S)-4-Amino-4-carboxybutyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]-1-pyridiniumyl}-L-norleucine | |
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3D model (JSmol) |
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4074277 | |
ChEBI | |
ChemSpider |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C24H40N5O8 | |
Molar mass | 526.611 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Desmosine is a component of elastin and cross links with its isomer, isodesmosine, giving elasticity to the tissue. Detection of desmosine in urine, plasma or sputum samples can be a marker for elastin breakdown due to high elastase activity related to certain diseases.[1][2]