Craniodiaphyseal dysplasia
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Craniodiaphyseal dysplasia (CDD), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy.
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Craniodiaphyseal dysplasia | |
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Other names | CDD or Lionitis |
Craniodiaphyseal dysplasia has an autosomal recessive pattern of inheritance[1] |
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These calcium deposits decrease the size of cranial foramina, and can decrease the circumference of the cervical spinal canal. In the few cases recorded, most died in childhood.