CHEK1
Protein-coding gene in humans / From Wikipedia, the free encyclopedia
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Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene.[5][6] Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response.[7] Activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.
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