Bromocresol green
Chemical dye and pH indicator / From Wikipedia, the free encyclopedia
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Bromocresol green (BCG) is a dye of the triphenylmethane family (triarylmethane dyes). It belongs to a class of dyes called sulfonephthaleins.[4] It is used as a pH indicator in applications such as growth mediums for microorganisms and titrations. In clinical practise, it is commonly used as a diagnostic technique. The most common use of bromocresol green is to measure serum albumin concentration within mammalian blood samples in possible cases of kidney failure and liver disease. In chemistry, bromocresol green is used in Thin-layer chromatography staining solutions to visualize acidic compounds.
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-2,1λ6-benzoxathiole-1,1(3H)-dione | |
Other names
3,3′,5,5′-Tetrabromo-m-cresolsulfonphthalein Bromcresol green | |
Identifiers | |
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3D model (JSmol) |
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Abbreviations | BCG |
ChEMBL | |
ChemSpider |
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ECHA InfoCard | 100.000.885 |
EC Number |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C21H14Br4O5S | |
Molar mass | 698.01 g·mol−1 |
Appearance | Beige to brown powder |
Odor | Odorless |
Melting point | 225 °C (437 °F; 498 K) decomposes[1] |
Sparingly soluble | |
Solubility in other solvents | Soluble in benzene; very soluble in ethanol and diethyl ether[2] |
Acidity (pKa) | 4.90[3] |
UV-vis (λmax) | 423 nm[1] |
Hazards | |
GHS labelling: | |
Warning | |
H315, H319, H335 | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Bromocresol green (pH indicator) | ||
below pH 3.8 | above pH 5.4 | |
3.8 | ⇌ | 5.4 |