Atrophic gastritis
Medical condition / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Atrophic gastritis?
Summarize this article for a 10 year old
Atrophic gastritis is a process of chronic inflammation of the gastric mucosa of the stomach, leading to a loss of gastric glandular cells and their eventual replacement by intestinal and fibrous tissues. As a result, the stomach's secretion of essential substances such as hydrochloric acid, pepsin, and intrinsic factor is impaired, leading to digestive problems. The most common are vitamin B12 deficiency possibly leading to pernicious anemia; and malabsorption of iron, leading to iron deficiency anaemia.[2] It can be caused by persistent infection with Helicobacter pylori, or can be autoimmune in origin. Those with autoimmune atrophic gastritis (Type A gastritis) are statistically more likely to develop gastric carcinoma, Hashimoto's thyroiditis, and achlorhydria.
Atrophic gastritis | |
---|---|
Other names | Type A gastritis[1] |
Atrophic gastritis | |
Specialty | Gastroenterology |
Type A gastritis primarily affects the fundus (body) of the stomach and is more common with pernicious anemia.[1] Type B gastritis primarily affects the antrum, and is more common with H. pylori infection.[1]