Angiotensin (1-7)
Chemical compound / From Wikipedia, the free encyclopedia
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Angiotensin (1-7) (C
41H
62N
12O
11; Molecular weight = 899.02 g/mol; H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH) is an active heptapeptide of the renin–angiotensin system (RAS).[citation needed]
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In 1988, Santos et al demonstrated that angiotensin (1-7) was a main product of the incubation of angiotensin I with brain micropunch biopsies[1] and Schiavone et al reported the first biological effect of this heptapeptide.[2]
Angiotensin (1-7) is a vasodilator agent affecting cardiovascular organs, such as heart, blood vessels and kidneys, with functions frequently opposed to those attributed to the major effector component of the RAS, angiotensin II (Ang II).[3]