Allylglycine
Chemical compound / From Wikipedia, the free encyclopedia
Allylglycine is a glycine derivative. It is an inhibitor of glutamate decarboxylase.[2] Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter.[3] Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.[4]
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
2-Aminopent-4-enoic acid | |
Identifiers | |
3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.028.809 |
PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C5H9NO2 | |
Molar mass | 115.13 g/mol |
Appearance | white crystalline powder |
Density | 1.098 g/mL |
Melting point | 265 °C (509 °F; 538 K) |
Boiling point | 231 °C (448 °F; 504 K) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
Convulsant |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
147-195 mg/kg (mice, intraperitoneal)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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