Alagille syndrome
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Alagille syndrome (ALGS) is a genetic disorder that affects primarily the liver and the heart. Problems associated with the disorder generally become evident in infancy or early childhood. The disorder is inherited in an autosomal dominant pattern, and the estimated prevalence of Alagille syndrome is 1 in every 30,000[1][2] to 1 in every 40,000 live births. It is named after the French pediatrician Daniel Alagille, who first described the condition in 1969.[3][4] Children with Alagille syndrome live to the age of 18 in about 90% of the cases.[5]
Quick Facts Other names, Specialty ...
Alagille syndrome | |
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Other names | Alagille–Watson syndrome (ALGS), hepatic ductular hypoplasia |
Alagille syndrome is inherited in an autosomal dominant manner | |
Specialty | Medical genetics, Gastroenterology, Cardiology |
Named after | Daniel Alagille |
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