User:Dltkddn1025/sandbox
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Liver cell damage (also known as hepatocellular injury) refers to biological or physical damage to the liver cells or hepatocytes as a result of different pathological changes. Liver cell damage involves apoptosis or necrosis of liver cells or hepatocytes. Common signs and symptoms can be fever, jaundice, right upper quadrant abdominal pain, fatigue and nausea. Causes of liver cell damage involve oxidative stress from free radicals and antioxidant consumption, immune responses against foreign substances and virus infections or nonspecific causes which can be environmental or genetic factors. Diagnosis of liver cell damage encompasses detections of biomarkers which are enzymes in the liver that reflect inflammation or hepatocyte damage condition. Therapeutic interventions of liver cell damage can be specific for liver cell damage originated from different causes. Examples of therapeutic interventions are liver transplantation, stem cell therapy, antioxidants, vaccinations and immunosuppressants.
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