Moexipril
Antihypertensive drug of the ACE inhibitor class / From Wikipedia, the free encyclopedia
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Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor)[1] used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.[2]
Quick Facts Clinical data, Trade names ...
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Trade names | Univasc |
AHFS/Drugs.com | Monograph |
MedlinePlus | a695018 |
Routes of administration | Oral |
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Bioavailability | 13-22% |
Protein binding | 90% |
Metabolism | Hepatic (active metabolite, moexiprilat) |
Elimination half-life | 1 hour; 2-9 hours (active metabolite) |
Excretion | 50% (faeces), 13% (urine) |
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Chemical and physical data | |
Formula | C27H34N2O7 |
Molar mass | 498.576 g·mol−1 |
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It works by inhibiting the conversion of angiotensin I to angiotensin II.[3]
It was patented in 1980 and approved for medical use in 1995.[4] Moexipril is available from Schwarz Pharma under the trade name Univasc.[3][5]