Tubocurarine chloride
Obsolete muscle relaxant / From Wikipedia, the free encyclopedia
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Tubocurarine (also known as d-tubocurarine or DTC) is a toxic benzylisoquinoline alkaloid historically known for its use as an arrow poison. In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation. Safer alternatives, such as cisatracurium and rocuronium, have largely replaced it as an adjunct for clinical anesthesia and it is now rarely used.
Quick Facts Clinical data, AHFS/Drugs.com ...
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AHFS/Drugs.com | International Drug Names |
MedlinePlus | a682860 |
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Routes of administration | IV |
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Bioavailability | 100% (IV) |
Protein binding | 50% |
Elimination half-life | 1–2 hours |
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Formula | C37H42Cl2N2O6 |
Molar mass | 681.65 g·mol−1 |
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