Toll-like receptor 5
Protein found in humans / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about TLR5?
Summarize this article for a 10 year old
Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene.[5] It is a member of the toll-like receptor (TLR) family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria.[6] It has been shown to be involved in the onset of many diseases, including Inflammatory bowel disease due to the high expression of TLR in intestinal lamina propria dendritic cells.[7][8] Recent studies have also shown that malfunctioning of TLR5 is likely related to rheumatoid arthritis,[9][10] osteoclastogenesis, and bone loss.[11] Abnormal TLR5 functioning is related to the onset of gastric, cervical, endometrial and ovarian cancers.[12][13]