Growth hormone–releasing hormone
Mammalian protein found in Homo sapiens / From Wikipedia, the free encyclopedia
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Growth hormone–releasing hormone (GHRH), also known as somatocrinin or by several other names in its endogenous forms and as somatorelin (INN) in its pharmaceutical form, is a releasing hormone of growth hormone (GH). It is a 44[1]-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus.
Quick Facts Identifiers, Symbol ...
Growth hormone releasing hormone | |||||||
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Identifiers | |||||||
Symbol | GHRH | ||||||
Alt. symbols | GRF, GHRF | ||||||
CAS number | 9034-39-3 | ||||||
NCBI gene | 2691 | ||||||
HGNC | 4265 | ||||||
OMIM | 139190 | ||||||
RefSeq | NM_021081 | ||||||
UniProt | P01286 | ||||||
Other data | |||||||
Locus | Chr. 20 p12 or q11.2-q12 | ||||||
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GHRH first appears in the human hypothalamus between 18 and 29 weeks of gestation, which corresponds to the start of production of growth hormone and other somatotropes in fetuses.[1]