Sodium-glucose transport proteins
Group of transport proteins / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Sodium-glucose transport proteins?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose passes into the urine (glucosuria) because SGLT are saturated with the filtered glucose.
Quick Facts solute carrier family 5 (sodium/glucose cotransporter), member 1, Identifiers ...
solute carrier family 5 (sodium/glucose cotransporter), member 1 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | SLC5A1 | ||||||
Alt. symbols | SGLT1 | ||||||
NCBI gene | 6523 | ||||||
HGNC | 11036 | ||||||
OMIM | 182380 | ||||||
RefSeq | NM_000343 | ||||||
UniProt | P13866 | ||||||
Other data | |||||||
Locus | Chr. 22 q13.1 | ||||||
|
Close
Quick Facts solute carrier family 5 (sodium/glucose cotransporter), member 2, Identifiers ...
solute carrier family 5 (sodium/glucose cotransporter), member 2 | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | SLC5A2 | ||||||
Alt. symbols | SGLT2 | ||||||
NCBI gene | 6524 | ||||||
HGNC | 11037 | ||||||
OMIM | 182381 | ||||||
RefSeq | NM_003041 | ||||||
UniProt | P31639 | ||||||
Other data | |||||||
Locus | Chr. 16 p11.2 | ||||||
|
Close
Quick Facts solute carrier family 5 (low affinity glucose cotransporter), member four, Identifiers ...
solute carrier family 5 (low affinity glucose cotransporter), member four | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | SLC5A4 | ||||||
Alt. symbols | SGLT3, SAAT1, DJ90G24.4 | ||||||
NCBI gene | 6527 | ||||||
HGNC | 11039 | ||||||
RefSeq | NM_014227 | ||||||
UniProt | Q9NY91 | ||||||
Other data | |||||||
Locus | Chr. 22 q12.1-12.3 | ||||||
|
Close