Organo anion transporter family
Family of transport proteins / From Wikipedia, the free encyclopedia
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Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the Solute Carrier Family (SLC) and the major facilitator superfamily.[1]
Quick Facts Organic-anion-transporting polypeptide (OATP) family, Identifiers ...
Organic-anion-transporting polypeptide (OATP) family | |||||||||
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Identifiers | |||||||||
Symbol | OATP | ||||||||
Pfam | PF03137 | ||||||||
InterPro | IPR004156 | ||||||||
TCDB | 2.A.60 | ||||||||
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The generalized transport reactions catalyzed by members of the OAT family are:
Anion (in) → Anion (out)
Anion1 (in) + Anion2 (out) → Anion1 (out) + Anion2 (in)