N,N'-Diallyl-L-tartardiamide
Chemical compound, polyacrylamide crosslinker / From Wikipedia, the free encyclopedia
N,N′-Diallyl-L-tartardiamide (DATD) is a crosslinking agent for polyacrylamide gels, e.g., as used for SDS-PAGE.[1] Compared to bisacrylamide gels, DATD gels have a stronger interaction with glass, and therefore are used in applications where the polyacrylamide gel acts as a "plug" structural component at the bottom of a gel electrophoresis apparatus, thereby preventing a weak discontinuous gel from sliding out from or otherwise moving within the apparatus.[1][2] Unlike bisacrylamide-polyacrylamide gels, DATD-polyacrylamide gels can be conveniently dissolved using periodic acid due to the presence of viscinal diols in DATD.[3] DATD is the slowest polyacrylamide crosslinker tested,[4] and has can act as an inhibitor of polymerization at high concentrations.[4][5][6]
Names | |
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Preferred IUPAC name
(2R,3R)-2,3-dihydroxy-N,N'-bis(prop-2-enyl)butanediamide | |
Identifiers | |
3D model (JSmol) |
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ECHA InfoCard | 100.055.688 |
PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C10H16N2O4 | |
Molar mass | 228.248 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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