Interleukin-1 receptor antagonist
Protein and coding gene in humans / From Wikipedia, the free encyclopedia
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The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene.[5][6]
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IL-1RA was initially called the IL-1 inhibitor and was discovered separately in 1984 by two independent laboratories.[7] IL-1RA is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds interleukin 1 family (IL-1), preventing IL-1's from sending a signal to that cell.