AFF2
Protein-coding gene in humans / From Wikipedia, the free encyclopedia
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AF4/FMR2 family member 2 is a protein that in humans is encoded by the AFF2 gene.[5] Mutations in AFF2 are implicated in cases of breast cancer.[6]
Quick Facts Identifiers, Aliases ...
AFF2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | AFF2, FMR2, FMR2P, FRAXE, MRX2, OX19, AF4/FMR2 family member 2, XLID109 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 300806; MGI: 1202294; HomoloGene: 136314; GeneCards: AFF2; OMA:AFF2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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CCG repeat expansions in this gene are associated with X-linked intellectual disability and specifically a syndrome known as Fragile XE mental retardation (FRAXE). FRAXE is one of the most common forms of non-syndromic X-linked intellectual disability. The gene is also known as FMR2 (Fragile Mental Retardation 2) after this condition.[7]