File:Protective_barriers_of_the_brain.jpg
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Summary
DescriptionProtective barriers of the brain.jpg |
English: Protective barriers of the brain. The collective term “blood-brain barrier” is used to describe four main interfaces between the central nervous system and the periphery. (i) The blood-brain barrier proper formed by tight junctions between the endothelial cells of the cerebral vasculature. It is thought that pericytes (peri.) are sufficient to induce some barrier characteristics in endothelial cells, while astrocytes (astro.) are able to maintain the integrity of the blood-brain barrier postnatally. (ii) The blood-CSF barrier formed by tight junctions between epithelial cells of the choroid plexus epithelial cells (note the plexus vasculature is fenestrated). Resident epiplexus (epi.) immune cells are present on the CSF-surface of the plexus epithelium. (iii) The outer CSF-brain barrier and the level of the pia arachnoid, formed by tight junctions between endothelial cells of the arachnoid vessels. (iv) The inner CSF-brain barrier, present only in early development, formed by strap junctions between the neuroependymal cells lining the ventricular surfaces. In the adult this barrier is no longer present. Both the blood-brain and CSF-brain barriers extend down the spinal cord. The CSF-filled ventricular system is depicted in blue, while CNS brain tissue is in brown. The lateral ventricular choroid plexuses are shown in red. Abbreviations: astro, astrocyte; bv, blood vessel; cpec, choroid plexus epithelial cell; csf, cerebrospinal fluid; peri, pericytes. |
Date | Published online: 2013-08-23 |
Source | Stolp HB, Liddelow SA, Sá-Pereira I, Dziegielewska KM and Saunders NR (2013) Immune responses at brain barriers and implications for brain development and neurological function in later life. Front. Integr. Neurosci. 7:61. doi: 10.3389/fnint.2013.00061 http://journal.frontiersin.org/article/10.3389/fnint.2013.00061/full |
Author | Stolp HB, Liddelow SA, Sá-Pereira I, Dziegielewska KM and Saunders NR |
Other versions | العربيَّة |
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Width | 2,126 px |
Height | 3,300 px |
Bits per component |
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Pixel composition | RGB |
Orientation | Normal |
Number of components | 3 |
Horizontal resolution | 72 dpi |
Vertical resolution | 72 dpi |
Software used | Adobe Photoshop CS5.1 Windows |
File change date and time | 10:05, 20 August 2013 |
Exif version | 2.21 |
Color space | Uncalibrated |
Date and time of digitizing | 06:46, 24 July 2013 |
Date metadata was last modified | 15:35, 20 August 2013 |
Unique ID of original document | uuid:9E3E5C9A8C81DB118734DB58FDDE4BA7 |