Feline coronavirus
Species of virus / From Wikipedia, the free encyclopedia
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Feline coronavirus (FCoV) is a positive-stranded RNA virus that infects cats worldwide.[2] It is a coronavirus of the species Alphacoronavirus 1, which includes canine coronavirus (CCoV) and porcine transmissible gastroenteritis coronavirus (TGEV). FCoV has two different forms: feline enteric coronavirus (FECV), which infects the intestines, and feline infectious peritonitis virus (FIPV), which causes the disease feline infectious peritonitis (FIP).
Feline coronavirus | |
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Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Pisuviricota |
Class: | Pisoniviricetes |
Order: | Nidovirales |
Family: | Coronaviridae |
Genus: | Alphacoronavirus |
Subgenus: | Tegacovirus |
Species: | |
Virus: | Feline coronavirus |
Strains[1] | |
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Feline coronavirus is typically shed in feces by healthy cats, and transmitted by the fecal-oral route to other cats.[3] In environments with multiple cats, the transmission rate is much higher compared to single-cat environments.[2] The virus is insignificant until mutations cause it to be transformed from FECV to FIPV.[2] FIPV causes feline infectious peritonitis, for which treatment is generally symptomatic and palliative only. The drug GS-441524 shows promise as an antiviral treatment for FIP, but at the moment it still requires further research.[4] The drug GC376 is also being studied and developed.