β-Thromboglobulin
Protein / From Wikipedia, the free encyclopedia
β-Thromboglobulin (β-TG), or beta-thromboglobulin, is a chemokine protein secreted by platelets.[1][2] It is a type of chemokine (C-X-C motif) ligand 7.[3] Along with platelet factor 4 (PF4), β-TG is one of the best-characterized platelet-specific proteins.[4] β-TG and PF4 are stored in platelet alpha granules and are released during platelet activation.[1][4][5] As a result, they are useful markers of platelet activation.[1][4] β-TG also has multiple biological activities, for instance being involved in maturation of megakaryocytes.[6]
Quick Facts Identifiers, Symbol ...
β-Thromboglobulin | |||||||
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Identifiers | |||||||
Symbol | CXCL7 | ||||||
Alt. symbols | CTAP3, CXCL7, SCYB7, TGB1, THBGB1 | ||||||
NCBI gene | 5473 | ||||||
HGNC | 9240 | ||||||
OMIM | 121010 | ||||||
RefSeq | NP_002695 | ||||||
UniProt | P02775 | ||||||
Other data | |||||||
Locus | Chr. 4 q13.3 | ||||||
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