2,6-Diaminopurine
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2,6-diaminopurine (2,6-DAP, also known as 2-aminoadenine) is a compound once used in the treatment of leukemia.[1] As the Z base, it is found instead of adenine (A) in the genetic material of some bacteriophage viruses.[2]
Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
7H-purine-2,6-diamine | |
Other names
2-aminoadenine; 2,6-DAP | |
Identifiers | |
3D model (JSmol) |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.016.006 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C5H6N6 | |
Molar mass | 150.145 g·mol−1 |
Appearance | White to yellow crystalline powder |
Density | 1.743 g/cm3 |
Melting point | 117 to 122 °C (243 to 252 °F; 390 to 395 K) |
2.38 g/L at 20 °C | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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In August 2011, a report, based on NASA studies with meteorites found on Earth, was published suggesting 2,6-diaminopurine and related organic molecules, including the DNA and RNA components adenine and guanine, may have been formed extraterrestrially in outer space.[3][4][5]